In 1818, two thermal springs with healing properties were discovered in the spot where the Grand Hotel Toplice stands today. Four years later, they were covered by a wooden shed and the first swimming complex in Bled was built. In 1850, the post superintendent Hoffmann of Ljubljana began building a small hotel next to the swimming complex located on the lakeshore, which he opened in 1854. He named Louisenbad after his wife Louise. The building was the predecessor of today's Grand Hotel Toplice. The owner also built spas next to the hotel which were previously poorly maintained. In 1870, the hotel was purchased by Jožef Luckmann, a businessman and director of the Kranj Savings Bank in Ljubljana who sold it just a few years later to Count Camillo Aichelberg who had great admiration for Bled. In 1875, he enlarged the hotel building significantly and renovated it in its entirety. From the very beginning, the hotel was a favourite destination for high society which remains the same to this very day. In 1889, Hotel Louisenbad with all of the associated buildings was bought by Gustav Valtrini who was previously a chef at the hotel. Valtrini managed the hotel with his wife Fanny. They devoted a lot of attention to the hotel's furnishings and guest comfort. Hotel was opulently furnished with valuable items from around the world. It was famed for excellent cuisine. They offered their guests thermal baths and healing treatments that involved drinking the water from the thermal spring. The water from the thermal springs was recommended for the treatment of anaemia, infections, neurodegenerative diseases, rheumatism and gout.

In 1919, the hotel was acquired by Jula Molnar who built additional edifices with the help of architect Franz Baumgartner in 1925. She named it Toplice. In 1932, a Roman spa-type swimming pool was built at Toplice featuring 30 cabins for 90 swimmers. Thermal water from the spring located under the hotel was channelled to the pool. King Aleksander proclaimed the Suvobor mansion his royal summer residence and the nearby Hotel Toplice became the meeting place for the highest echelons, politicians, noblemen and other important people. Jula, who only finished a civic school (Bürgerschule), was nevertheless a very capable director of a premium hotel thanks to her natural intelligence and practical experience. She was able to converse with both the simple people and her renowned guests. Employees adored her. She was good and fair to everyone which is why they respected her and remained loyal to her. As a farmer's daughter, she had never heard of golf, but men came from England and Australia who knew a lot about the game and so the first golf course was developed at Bled. The kitchen was famous for excellence and the nearby wooden cafe was famed for desserts, good coffee and ice cream.

Hotel Toplice, the first hotel with its own indoor swimming pool, is still the best-known hotel in Bled that keeps the memory of the numerous famous people and many important events. 

Some say that the heart of the Grand Hotel Toplice is the hotel salon that opens up to the magnificent view of the lake and the Bled Castle, but we would argue that it is the guests that are the heart of our hotel. Without them, it would simply not be what it is. We wanted to honour their exceptionality with a special visitor book where many an influential and important guest have signed their name. Perusing the book will take you into far-away lands across the Big Pond, kingdoms and important global political institutions as well as through the worlds of film, sports and arts. The Grand Hotel Toplice has hosted kings, more than 20 presidents, more than 20 government representatives, and tens of ministers, Nobel Prize winners, intellectuals, creatives, scientists, athletes, artists and movie stars. Each visit is a special story in and of itself.

Some of the famous people who stayed at the hotel include: Bobby Fischer (chess master and world champion, 1959), Arthur Miller (US playwright, 1965), Pablo Neruda (poet and Nobel Prize winner, 1965), Agatha Christie (writer, 1967), Franz Josef Strauss (Minister-President of Bavaria, 1969), Hussein (Jordanian King, 1978), Simon Wiesenthal (Nazi hunter), Heinrich Harrer (Austrian Alpine climber and writer), Carlo Ponti (film producer), Vivien Leigh (actress), Cliff Richards (musician, 1989), Ronald Sega (astronaut, 1994), President Süleyman Demirel (Turkish President, 1997), Garry Kasparov (chess master and world champion, 2002),  Donald Trump (current US President), Paul McCartney (musician, 2005), Ban Ki-moon (UN Secretary-General, 2008), Anže Kopitar (Stanley Cup winner, 2012).